Summary of Core Facilities

Cognitive Function

Object Recognition

Object Placement

Social Discrimination Memory

Spontaneous Alternation

• Morris Water Maze

• Sensorimotor gaiting

• Radial Arm Maze

• Conditioned Taste Aversion

Labyrinth Maze

Affective / Emotional Behaviors

Social Interaction

Social Preference

Transmission of Food Preferences

Reproductive and mating behavior

Open Field

Marble Burying

Elevated Plus Maze

• Light/Dark Box

• Acoustic Startle

Porsolt (Forced Swim) Test

Maternal behavior

Novelty Supression of Feeding



Tests of Analgesia

Von Frey

Cold Tail Flick


Sensorimotor Function

Open Field


Grip Strength

Gait analysis and toe spread

Balance Beam

• Visual Placing

• Visual Cliff

• Pupil dilation

Tape removal test



Functional Observation Battery

Estrous Cycle Staging

• Behavioral Tracking software

• Conditioned Place Preference

• Grooming

• Stereotypies

Developmental milestones (pups)

Homing (pups)

Play (juvenile)


Gait Analysis

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Mice or rats receive several pre-training trials during which they are habituated to a runway to foster reliable crossing of the runway during the test. The start of the runway is brightly lit and the end contains a darkened enclosed chamber with Cocoa Krispies cereal pieces. Immediately after the pre-training sessions, footprints are recorded on a white paper on the runway floor after applying non-toxic tempera paint to the paws. Front paws are painted red and rear paws blue. Subjects are then allowed to walk down the runway, and 4 sets of footprints were collected for each animal. The footprint patterns were analyzed using the program Image J (NIH). Typical measures analyzed includ stride length, foot drags, the number of missteps, foot base and others.